Antofagasta Region Vacation Packages

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Top vacation destinations in Antofagasta Region

FlightsFlightsHotelsHotels

San Pedro de Atacama

San Pedro de Atacama

Antofagasta Region Hotel Deals

Diego de Almagro San Pedro de Atacama

Diego de Almagro San Pedro de Atacama

3 out of 5
Toconao 460 San Pedro de Atacama Antofagasta
Fully refundableReserve now, pay when you stay
The price is CA $144 per night from May 18 to May 19
CA $144
CA $144 total
May 18 - May 19
8.2/10 Very Good! (382 reviews)
Though the hotel chain Diego de Almagro is good, the one at SPA is not up to expectations. Wifi only in lobby, tv but no cable or wifi, pool too cold to use, bad information... The location, breakfast and room are ok. It is better than local hostales, but not a good hotel as it is promoted

Reviewed on May 5, 2026

Diego de Almagro San Pedro de Atacama
Hotel La Casa de Don Tomas

Hotel La Casa de Don Tomas

3 out of 5
Calle Tocopilla Sitio 18 San Pedro de Atacama
The price is CA $287 per night from May 19 to May 20
CA $287
CA $287 total
May 19 - May 20
Hotel La Casa de Don Tomas
Terrado Suites Antofagasta

Terrado Suites Antofagasta

4 out of 5
Baquedano 015 Antofagasta Antofagasta
Fully refundableReserve now, pay when you stay
The price is CA $98 per night from May 15 to May 16
CA $98
CA $98 total
May 15 - May 16
8.4/10 Very Good! (317 reviews)
Good breakfast, welcoming and helpful staff, nice restaurant. Great views from the room.

Reviewed on Apr 10, 2026

Terrado Suites Antofagasta
See all 315 properties in Antofagasta Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Frequently asked questions

How much does an Antofagasta Region vacation package cost?
From as low as . Yes, you read that right. Our Antofagasta Region packages are the best way to stretch your budget. Combine your hotels, flights and car rentals and discover this lively destination.
How do I get a cheap travel package to Antofagasta Region?
Our Antofagasta Region vacation packages promise plenty of savings for the savvy traveler. For the best deals, simply bundle your hotel, flights and activities into an affordable package. But impressive bargains are only the start of your next unforgettable adventure. Book with Expedia and you'll have more than 550 airlines and 1,000,000 properties throughout the world to pick from. Whatever your budget, there's a package that's perfect for you.
What are the top hotels in Antofagasta Region?
Have a look at ibis Antofagasta and NH Antofagasta. They're the first choice for lots of travelers to Antofagasta. If San Pedro de Atacama is on your travel itinerary, Park Hotel Calama and Noi Casa Atacama are cozy options.
How far in advance should I book my Antofagasta Region vacation?
It can be tricky to know when is the ideal time to book your trip to Antofagasta Region. But typically the earlier you book, the better the prices. Sometimes, you can reserve your flights and hotels up to a year before your departure date. If you're considering a last-minute getaway, no need to stress! There are fabulous deals featured on Expedia every single day.
What does an Expedia Antofagasta Region travel package include?
From hotels and airfares to rental cars, Expedia can help you shape an Antofagasta Region package that's perfect for you. Vacationing for a week or two? Consider a rental car, hotel and flight bundle. If you're taking a short break, a flight and hotel deal could be more your style. Activities can also be added once you've made your booking. Our vacation packages make it simple to save and plan.
What should I know before booking an Antofagasta Region travel package?
Tailor deals to suit your budget with an Expedia package. Airfares, hotels, rental cars — we're a one-stop shop for all of them. You'll save precious dollars just for bundling your bookings. Whether you're embarking on a skiing adventure or drinking cocktails on a beach, your perfect getaway is just clicks away.
Can I choose my airline with an Antofagasta Region Expedia vacation package?
Expedia has access to more than 550 airline partners worldwide, so you sure can! Simply select your preferred carrier and put together the perfect Antofagasta Region trip.
If I'm not able to travel, can I cancel my Antofagasta Region vacation package?
Whether it's your flight or hotel, you can cancel and rebook it. Locked in your Antofagasta Region vacation package in the last 24 hours? You may be able to make changes at no cost. For bookings older than that, you may be charged a fee by your hotel, airline or car rental company. For further information, visit our Customer Service Portal. We'll help you every step of the way.

Discover the most popular places to visit in Antofagasta Region

Valley of the Moon

Valley of the Moon

5/5(14 reviews)

Treat your eyes to the variety of colors in a deserted valley that looks like a scene from a science fiction movie.

Valley of the Moon

Plaza de San Pedro de Atacama

4/5(13 reviews)

You can find out about the history of San Pedro de Atacama when you stop by Plaza de San Pedro de Atacama. You can seek out the local tours in this quaint area.

Plaza de San Pedro de Atacama

Piedra del Coyote Overlook

4/5(1 review)

Explore the great outdoors at Piedra del Coyote Overlook, a lovely green space in San Pedro de Atacama. You can seek out the local tours in this quaint area.

Piedra del Coyote Overlook

What to do in Antofagasta Region

Astronomical Experience with Astrophotography in Atacama

Astronomical Experience with Astrophotography in Atacama

CA $58
per adult
Astronomical Experience with Astrophotography in Atacama
San Pedro de Atacama: Etno-Stargazing Tour with Transfer

San Pedro de Atacama: Stargazing experience

CA $53
per adult
San Pedro de Atacama: Stargazing experience
Tour to the Valley of the Moon San Pedro de Atacama

Tour to the Valley of the Moon San Pedro de Atacama

CA $48
per adult
94% of travellers recommend
Tour to the Valley of the Moon San Pedro de Atacama
See all activities in Antofagasta Region
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.